Imaging for biology and health (IBS)
Leader
| Emmanuel FORT Tel.: +33 (0)1 80 96 30 35  |
Co-leader
| Ignacio IZEDDIN Tel.: +33 (0)1 80 96 30 75  |
Permanent staff
| Michael ATLAN Tel.: +33 (0)1 80 96 30 36  |
| Pedro BARAÇAL DE MECÊ Tel.: +33 (0)1 80 96 30 51  |
| Claude BOCCARA Tel.: +33 (0)1 80 96 30 44  |
| Maïmouna BOCOUM Tel.: +33 (0)1 80 96 30 76  |
| Clément CABRIEL Tel.: +33 (0)1 80 96 30 59  |
Bruce DENBY |
| Emmanuel FORT Tel.: +33 (0)1 80 96 30 35 |
| Ros-Kiri ING Tel.: +33 (0)1 80 96 30 41  |
| Ignacio IZEDDIN Tel.: +33 (0)1 80 96 30 75 |
| François RAMAZ Tel.: +33 (0)1 80 96 30 47  |
| Olivier THOUVENIN Tel.: +33 (0)1 80 96 30 51  |
News
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Single-emitter super-resolved imaging of radiative decay rate enhancement in dielectric gap nanoantennas Córdova-Castro, R. M., B. Van Dam, A. Lauri, S. A. Maier, R. Sapienza, Y. De Wilde, I. Izeddin, and V. Krachmalnicoff Light: Science and Applications 13, no. 1 (2024) 
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Real-time acousto-optic imaging using high-peak-power long-pulsed illumination Figliolia, F., Q. Liu, S. Janicot, P. Georges, G. Lucas-Leclin, J. P. Huignard, F. Ramaz, J. M. Tualle, and M. Bocoum Optics Letters 49, no. 21, 5993-5996 (2024)
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Multi-spectral reflection matrix for ultrafast 3D label-free microscopy Balondrade, P., V. Barolle, N. Guigui, E. Auriant, N. Rougier, C. Boccara, M. Fink, and A. Aubry Nature Photonics 18, no. 10, 1097-1104 (2024)
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Aberration compensation in Doppler holography of the human eye fundus by subaperture signal correlation Bratasz, Z., O. Martinache, J. Sverdlin, D. Gatinel, and M. Atlan Biomedical Optics Express 15, no. 10, 5660-5673 (2024)
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Presentation of the thematics
The IBS theme studies biological processes and tissues from the nanoscopic to the macroscopic scale. By studying in depth the interaction between different waves and biological matter, new non conventional imaging techniques are being developed. Super-resolution imaging is used to probe the organisation of matter at the single molecule scale and to understand the transport of these molecules in the cell environment, in particular in the nucleus. The full-field optical imaging team is interested in the organisation of biological tissues using label-free interferometric microscopy techniques to study the viability of organism’s cells and tissues for applications in both fundamental biology and in vivo medical diagnostics. The Holographic Doppler Imaging team develops new techniques to quantify blood flow in the retina of human patients. However, the optical approaches presented above are limited to shallow penetration depths in the human body (except from the transparent eye). In order to probe biological tissues at greater depths, it is becoming necessary to use other types of waves, in particular acoustic waves. Acousto-optic imaging enables tissue to be imaged with optical contrast at a depth of several millimetres by tagging the photons that are multiply scattered using acoustic waves. Finally, the use of acoustic waves enables the surface motion team to map vibratory deformations of the thorax in a non-contact, non-invasive manner.
